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Characteristics of eyes with good visual acuity at 5 years after initiation of treatment for age-related macular degeneration but not receiving treatment from years 3 to 5: Post hoc analysis of the CATT randomized clinical trial

JAMA Ophthalmology Feb 03, 2020

Scoles D, Ying GS, Pan W, et al. - Researchers conducted this case-control study to determine the features of eyes in the Comparison of Age-Related Macular Degeneration Treatments Trials (CATT) that retained good vision despite receiving no therapy for 3 years after release from the 2-year CATT treatment protocol. Among 625 eyes with neovascular age-related macular degeneration at baseline and a visual acuity measurement at year 5, 40 were involved in the examination. The data presented in this work showed a small percentage (40 [6.4%]) retained a visual acuity letter score of 68 (Snellen 20/40) or better with no treatment for at least 3 years. Findings from this study showed that, after 2 years of protocol management, a minority of participants with neovascular age-related macular degeneration maintained good vision even without treatment indicating that not all eyes with this condition will need care forever.
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