Goto Y, Thike AA, Ong CCH,, et al. - Researchers tried to find out the characteristics, clinical behaviour and role of biomarkers (androgen receptor (AR), oestrogen receptor beta (ERβ) and p53) in metastatic triple-negative breast cancer (TNBC). This study conducted immunohistochemistry for AR, ERβ and p53 on 125 primary TNBCs with known metastasis and associated with clinicopathological parameters and outcome. They carried out AR and p53 mRNA profiling on 34 tumours from the same series and correlated with outcomes. This results of this study showed that metastatic TNBC harboured aggressive behaviour and displayed predominantly visceral metastasis with most metastatic events occurring without intervening local recurrences. A significant association was found between a combinational phenotype of AR-ERβ+p53+ and poorer OS.