Barrabes JA, et al. - Researchers analyzed consecutive patients hospitalized with suspected acute coronary syndrome (ACS) as the primary diagnosis to evaluate characteristics on admission and in-hospital and 6-month mortality of patients discharged with other diagnoses and to compare this subgroup with true ACS patients. They noted that patients with other diagnoses vs true ACS patients were younger, more often female, and had less cardiovascular risk factors. They reported a lack of confirmation of the diagnosis in a non-negligible proportion of patients hospitalized with suspected ACS. A bimodal pattern of prognosis was observed in these patients; those with non-specific chest pain had excellent prognosis but the rest had worse prognosis than that of true ACS patients. The findings call for efforts to ensure prompt detection and early risk stratification of these patients allowing appropriate management decisions.