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Characteristics and outcomes of children with coronavirus disease 2019 (COVID-19) infection admitted to US and Canadian pediatric intensive care units

JAMA May 15, 2020

Shekerdemian LS, Mahmood NR, Wolfe KK, et al. - Researchers sought to present an early description and characterization of COVID-19 infection in North American pediatric intensive care units (PICUs). They conducted a cross-sectional study including children positive for COVID-19 admitted to 46 North American PICUs from March 14 to April 3, 2020. Admission of 48 children [25 (52%) males; the median (range) age: 13 (4.2-16.6) years] to 14 PICUs was reported in the US and none in Canada. Preexisting underlying medical conditions were identified in a total of 40 children (83%); 35 (73%) children presented with respiratory symptoms, and 18 (38%) needed invasive ventilation, and the hospital mortality rate was 4.2%. Per this early study, COVID-19 can result in a significant disease burden in children. However, children less frequently experienced severe illness, and had better early hospital outcomes when compared with adults.

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