Clare R, et al. - In this retrospective cohort study, researchers examined patients with spontaneous coronary artery dissection (SCAD) to determine the features and long-term clinical outcomes in these subjects. They also investigated factors related to recurrent SCAD. Out of 26,598 patients hospitalized with a primary diagnosis of acute myocardial infarction, 208 (0.78%) were diagnosed with SCAD. Younger subjects and women developed SCAD more often. Less prevalence of hypertension, hyperlipidemia, obesity, and diabetes mellitus was seen with SCAD. Lower risk of death was observed in patients with SCAD among patients with acute myocardial infarction, mostly due to younger age, female sex, and low prevalence of atherosclerotic risk factors in SCAD patients. Following the initial presentation, risk of recurrent SCAD was persistent over the years. A higher risk for recurrent SCAD was observed in patients with fibromuscular dysplasia and migraine.