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Changes in the profile of circulating HDL subfractions in severe obese adolescents following a weight reduction program

Nutrition, Metabolism & Cardiovascular Diseases Feb 12, 2021

Montero D, Dutheil F, Walther G, et al. - Researchers analyzed the complete lipoprotein profile of severely obese adolescents in order to identify subfractions with diagnostic value for future cardiovascular disorders. Twenty-eight obese, comorbidity-free adolescents were admitted into a program for weight reduction. At the beginning and at the end of the study, circulating lipoproteins and glycaemia were assessed by conventional blood analysis as well as by using lipoprotein electrophoresis. Altogether, obese adolescents without comorbidities do not appear to develop clear dyslipidemia. Low values of high-density lipoprotein subfractions may, however, be considered as candidate predictors for the potential development of the cardiovascular disease. For this cause, to overcome this pathology, diet and exercise are essential methods.

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