Danielewska ME, et al. - Researchers examined if changes in the spectral content of the corneal pulse (CP) signal, measured in vivo in primary open-angle glaucoma (POAG) patients, indirectly reflect changes in corneal biomechanics after canaloplasty. They performed standard ophthalmic examinations in 15 eyes of 15 POAG patients who underwent canaloplasty combined with phacoemulsification before washout, preoperatively, at days 1, 7, and 1, 3, 6, and 12 months after surgery. Between the pre-washout and the pre-operative stages, they observed a decrease in the amplitude of the first harmonic and an increase in the normalized amplitude of the third harmonic (A_CP3n) of the CP signal. As per observations, changes in the A_CP3n value reflect changes in corneoscleral stiffness caused by surgery. Hence, monitoring of postoperative corneal biomechanics could be done indirectly using this supporting indicator that can be used to determine the time at which measures of intraocular pressure are no longer biased by the changed cornea boundary conditions caused by canaloplasty.