Trinh S, et al. - In this retrospective study, researchers compared adjusted mean estimated glomerular filtration rates (eGFR; mL/min/1.73 m²) of patients with chronic hepatitis B virus (HBV) infection treated with tenofovir disoproxil fumarate (TDF) vs patients treated with entecavir. Findings suggested no association of TDF with a higher risk of worsening renal function during short- or intermediate-term follow-up periods, among patients without significant renal impairment. A significant renal decline was among patients given TDF compared to patients given entecavir for patients with baseline renal impairment.