Zhang YP, et al. - Physicians designed this study to assess the value of change in quantitative CT image features belonging to the non-solid component of ground-glass nodules (GGNs) for the differentiation of invasive GGN (minimally invasive adenocarcinoma [MIA] and invasive adenocarcinoma [IA]) from benign and adenocarcinoma in situ (AIS) lesions. The diameter of benign and AIS and invasive GGNs significantly increased in the follow-up procedure of GGNs.