Leskinen T, et al. - The link between change in physical activity over time and accumulation of cardiometabolic risk factors was assessed among cardio-metabolically healthy participants (mean age 43.3 (SD 8.7) years, 85% women), using cumulative logistic regression for data analysis. Physical activity was assessed using four-item survey measure and was expressed as weekly metabolic equivalent (MET) hours in Time 1, 2, and 3. The outcome was the number of incident cardiometabolic risk factors (hypertension, dyslipidemia, diabetes, and obesity) at Time 4. As per findings, even a modest long-term increase in physical activity was shown to be related to attenuation in cardiometabolic risk whereas decrease in physical activity was found to be associated with increased risk.