Abdelrahman N, et al. - Investigators delineated the relationship between achievement of inactive disease and clinical remission with disease activity at presentation and time to diagnosis in a national cohort of juvenile-onset systemic lupus erythematosus (JSLE) patients. Among subjects achieving inactive disease vs those who did not, at 1 year and final follow-up, they did not observe statistically significant variations with respect to the time of diagnosis and disease activity at presentation. They found that most of the cases failed to reach the proposed criteria for inactive disease and consistently required immunosuppressive therapy indicating a high burden of disease in JSLE despite immunosuppressive treatment.