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CHA2DS2-VASc score predicts atrial fibrillation recurrence after cardioversion: Systematic review and individual patient pooled meta-analysis

Clinical Cardiology Feb 17, 2019

Vitali F, et al. - Researchers performed this systematic review and individual patient pooled meta-analysis to investigate whether early arrhythmia recurrence following atrial fibrillation (AF) cardioversion could be predicted by congestive heart failure or left ventricular systolic dysfunction (CHA2DS2-VASc) score. Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines were followed. From PubMed, Cochrane Library, and Biomed Central, they identified observational trials in patients with AF undergoing cardioversion, and clinical studies with available data on recurrence of AF and available data on CHA2DS2-VASc score. They also carried out univariate and multivariate logistic regression. The analysis included 2,889 patients, of whom 61% were male, 50% had hypertension, 12% had diabetes, and 23% had a history of ischemic heart disease. In the first 30 days following electrical or pharmacological cardioversion, CHA2DS2-VASc score was able to predict early recurrence of AF. Independent predictors of early recurrence of AF were chronic kidney disease, peripheral artery disease, previous use of beta blockers, and CHA2DS2-VASc score > 2, as seen in the multivariate analysis.

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