Khattab MF, et al. - A prospective cohort study was conducted to compare the clinical and radiographic outcomes of stand-alone polyetheretherketone (PEEK) cage with the anchored cage with screws for single-level anterior cervical discectomy and fusion (ACDF). This study included a total of 50 individuals who underwent single-level ACDF for cervical degeneration, with radiculopathy or myelopathy, between January 2012, to January 2014, at a single institution. Researchers assigned 21 individuals to the stand-alone cage group (group 1) and 29 to the anchored cage with a screws group (group 2). They performed Neck Disability Index (NDI), Visual Analogue Scale (VAS) of the arm and neck, radiographic segmental cervical angle (CA), and disc height assessments preoperatively, at 6 mo, and at 2 yr postoperatively. It was noted that the anchored cage with screws has some advantage compared with the stand-alone PEEK cage in avoiding dysphagia and restoring disc space height and cervical lordosis for one-level ACDF. This study indicated that the anchored spacer may be a good substitute for the stand-alone cage in one-level ACDF.