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Cervical pessary vs vaginal progesterone for the prevention of preterm birth in women with a twin pregnancy and a cervix <38 mm: A randomized controlled trial

American Journal of Obstetrics and Gynecology Jan 17, 2018

Dang VQ, et al. - Researchers aimed to investigate the relative effectiveness of cervical pessary and vaginal progesterone for the prevention of preterm birth (PTB) in twin pregnant women with a cervical length (CL) <38 mm. In this study, compared to vaginal progesterone, cervical pessary did not reduce PTB <34 weeks in these women. However, A significant reduction in PTB <34 weeks and better neonatal outcomes after the use of cervical pessary were observed in a prespecified subgroup of women with a CL <25th percentile.
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