Park JS, You Y, Ahn HJ, et al. - In this prospective single-centre observational study involving 41 individuals, researchers examined neurologic outcomes correlated with CSF lactate dehydrogenase (LDH) levels in out-of-hospital cardiac arrest (OHCA) survivors who had target temperature management (TTM). For this analysis, CSF and serum LDH samples were obtained instantly (LDH0) and at 24 (LDH24), 48 (LDH48), and 72 h (LDH72) after the return of spontaneous circulation (ROSC). Data reported that 21 patients had a poor neurologic outcome. At 48 h, the CSF LDH level was a highly specific and sensitive marker for the 3-month poor neurologic result. It may provide a useful predictive marker for neurological outcome in TTM-treated OHCA survivors.