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Cerebral perfusion is perturbed by preterm birth and brain injury

American Journal of Neuroradiology Jul 15, 2018

Mahdi ES, et al. - Researchers compared global and regional CBF in preterm infants with and without brain injury on conventional MR imaging using arterial spin-labeling during the third trimester of ex utero life, as well as examined the association between clinical risk factors and CBF. For this investigation, preterm infants younger than 32 weeks' gestational age and <1500 g were prospectively recruited and performed arterial spin-labeling MR imaging studies. Early disturbances in global and regional CBF in preterm infants following brain injury were reported. As per data, regional cerebral perfusion alterations were evident in the thalamus and pons, implying regional vulnerability of the developing cerebro-cerebellar circuitry.
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