Arteaga DF, et al. - In this prospective study involving 20 patients with intracranial atherosclerotic arterial disease (ICAD) experiencing a stroke within 45 days of study enrollment and 10 healthy controls, researchers determined whether shifting of cerebral blood flow (CBF) territories in response to changes in cerebral perfusion pressure (CPP) can provide a marker for stroke risk. In patients who met endpoint criteria relative to controls and patients who did not meet endpoint criteria, shifting indices were significantly higher. Findings suggested that flow territory shifting could provide a marker of recurrent risk of stroke in symptomatic ICAD patients on standard-of-care medical management therapies.