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Central vs ambulatory blood pressure for predicting mortality and cardiovascular events in hemodialysis patients: A multicenter cohort study

Journal of Hypertension Dec 14, 2021

Liu W, Ye Y, Wang L, et al. - In dialysis patients, ambulatory blood pressure (BP) is superior to central BP for risk stratification. All-cause death and cardiovascular events in dialysis patients can be predicted by central BP but its prognostic value does not outperform ambulatory peripheral BP.

  • Central BP in the general population could be better than peripheral BP in risk assessment, and there is no comparison of office central BP with ambulatory BP regarding risk stratification in the dialysis population.

  • This is a multicenter prospective study wherein 368 dialysis patients were recruited and 366 had central BP measurement done.

  • For defining hypertension, a moderate agreement was evident between central BP and ambulatory BP, with wide limits of agreement in Bland—Altman analysis.

  • Post-follow-up, central pulse pressure, ambulatory SBP and ambulatory pulse pressure were found linked with all-cause death, whereas MACE (major adverse cardiovascular events) was significantly predicted by all BP parameters, except for predialysis DBP.

  • The best candidate for prediction of both all-cause death and MACE was ambulatory pulse pressure.

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