Eisenberg M, et al. - Experts undertook an assessment of the factors imparting the greatest risk of central line-associated bloodstream infection (CLABSI) in children with intestinal failure and fever presenting to an Emergency Department (ED). Furthermore, they aspired to examine the existence of a low-risk group possibly not requiring the standard treatment of admission for 48 hours on intravenous antibiotics pending culture results. High rates of CLABSI were discovered among these children. Findings disclosed a strong link between higher temperature in the ED, lower white blood cell count, and lower platelet count with CLABSI. Nonetheless, subjects without these risk factors frequently reported positive blood cultures. Hence, antibiotics were recommended to all children with intestinal failure and fever until CLABSI was ruled out.