Martinez T, Baugnon T, Vergnaud E, et al. - Researchers conducted this retrospective monocentric cohort study to assess the impact of a 4% chlorhexidine (CHG4%) bathing on the occurrence of central‐line‐associated bloodstream infection (CLABSI) and to detect risk factors for CLABSI in the population. This investigation was carried out in the paediatric surgical intensive care unit at the Necker Enfants Malades Hospital, Paris, France. Participants in the study all hospitalised patients (n = 775) with central venous catheters (CVCs) in 2015. Data reported that CLABSI incidence rates in 2014 and 2015 were 6.1 and 2.3/1000 days CVC, respectively. The data presented in this work showed a significant reduction in CLABSI incidence following the implementation of a targeted CHG4% bathing protocol. The risk factors for CLABSI were presence of invasive medical device (IMD), S. aureus colonisation, immunosuppression, age <1 year and carrying duration >16 days. As for the literature, the role of IMD in CLABSI prevention seems to be underestimated.