Kim J, Cho YJ, Ryu JY, et al. - Researchers conducted the study for analyzing the clinical significance of cyclin-dependent kinase 7 (CDK7) expression and its potential as a therapeutic target in epithelial ovarian cancer (EOC). CDK7 expression has been studied in 436 ovarian tissues including normal to metastatic ovarian tumors utilizing immunohistochemistry, and its clinical implications have been examined. Mechanistic interrogation of CDK7 showed that it is significantly related to an aggressive phenotype of EOC, and it has independent prognostic power for EOC recurrence. In addition, for patients with EOC, whether platinum-sensitive or resistant, CDK7 may be a potential therapeutic target.