Chen J, et al. - Authors gauged the level of infiltration of CD8+ tumor-infiltrating lymphocytes (TILs) including high and low density in lung sarcomatoid carcinoma (LSC). They also assessed their clinicopathological significance. Paraffin-embedded tissue sections from 100 LSC patients was assessed for density of CD8+ TILs via by immunohistochemical staining. For LSC patients, CD8+ TILs could be an effective prognostic index, and a better outcome may be forecast by a high density of CD8+ TILs in tumor tissue. They noted 92.3 months was the mean overall survival (OS) of LSC patients with a high density of CD8+ TILs, which was significantly higher than the 31.2 months seen in patients with a low density of CD8+ TILs. For OS time of LSC patients, the density of CD8+ TILs was an independent prognostic factor, as confirmed by the Cox regression multivariate analysis.