Huang DW, et al. – The scientists explored the CD155 expression and its correlations with clinicopathologic data, angiogenesis, and prognosis in the patients with cholangiocarcinoma (CCA). They illustrated that upregulated CD155 was associated with aggressive clinicopathologic characteristics, angiogenesis, and poor prognosis in CCA. Hence, it could be used as a promising prognostic biomarker for the CCA patients.