Speigl L, et al. - Researchers, in this study, aimed to identify differences in the immune systems of breast cancer patients compared to healthy women that may provide insight into the potential targets for immunotherapy and thus may assist its clinical implementation. Results here underscored the potential importance of cells with monocytic myeloid-derived suppressor cell (mMDSC) phenotypes, identifiable already at early stages of the disease. Thereby providing a basis for identifying possible new therapeutic targets to heighten anti-cancer immunity.