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Causes of death among cancer patients in the era of cancer survivorship in Korea: Attention to the suicide and cardiovascular mortality

Cancer Medicine Jan 29, 2020

Oh CM, Lee D, Kong HJ, et al. - Given a rise in noncancer deaths is anticipated due to improved cancer survival, but detailed causes of death are rarely explained, and shifting landscapes in mortality patterns and noncancer mortality risks in patients with cancer need assessment, so, researchers used data from the 2000-2016 national cancer registry in Korea (n = 2,707,520) to determine cancer as well as noncancer-related causes of death and to characterize the principal causes of death and proportionate mortalities over time. They found that patients with liver (86%) and lung (70%) cancers and female patients with breast cancer (77%) had high proportionate mortalities of primary cancer among overall deaths even at 5 to 10 years post-diagnosis, whereas a decrease of proportionate mortalities to ≤ 50% was seen in patients with stomach (men, 39%; women, 48%), prostate (47%), and female thyroid (27%) cancers. From 2000 to 2016, patients with cancer exhibited a 20-fold rise in cardiovascular disease deaths. Cancer patients had a higher risk of suicide compared with the general population. According to findings, deaths from primary cancer continue to be a major concern; however, there is a need for follow-up for both cancer and noncancer-associated health problems in cancer survivors, particularly regarding suicide and cardiovascular deaths.
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