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Carrier prevalence and risk factors for colonization of multiresistant bacteria in Danish emergency departments: A cross-sectional survey

BMJ Open Jul 03, 2019

Skjøt-Arkil H, et al. - Through a multicentre descriptive and analytic cross-sectional survey of 8 emergency departments (EDs), four clinical microbiology departments in Denmark and 5,117 patients, the researchers explained the carrier prevalence and demographic variation of four different multiresistant bacteria (MRB, [methicillin-resistant Staphylococcus aureus {MRSA}, carbapenemase-producing enterobacteria {CPE}, extended-spectrum beta-lactamase-producing enterobacteria {ESBL} and vancomycin-resistant enterococci {VRE}]) among acute patients in Danish EDs, and investigated the association of MRB carriage to a range of possible risk factors. Two hundred and sixty-six individuals were colonized with at least one MRB. Between male and female patients, age groups and the university and regional hospitals, no marked difference was recognized. Out of the 266 patients, Only 5 with MRB were colonized with two of the involved bacteria and none with more than two. The prevalence of CPE, MRSA, VRE, ESBL was 0.1%, 0.3%, 0.4% and 4.5%, respectively. Hence, every 20th patient which appeared at a Danish ED brought MRB to the hospital. In the ED, the most common MRB was ESBL. Also, prior antibiotic treatment, previous hospital admission, chronic respiratory infections, urinary catheters use and travel to Asia, Oceania or Africa were the risk factors for MRB carriage.
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