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Carotid plaque neovascularization detected with superb microvascular imaging ultrasound without using contrast media

Stroke Nov 07, 2019

Zamani M, et al. - Via involving 31 patients (22 patients were symptomatic and 9 asymptomatic) with > 50% carotid stenosis, researchers evaluated the feasibility of superb microvascular imaging for the detection of intraplaque neovascularization (IPN). All participants in the study had conventional carotid ultrasound, CEUS, superb microvascular imaging (SMI), and blood tests. A significant positive association was found between an IPN visual 5-level classification of SMI and a semiquantitative analysis of CEUS. Higher SMI grade plaques had higher numbers of neovessels quantified at histology. Hypoechoic plaques on both CEUS and SMI had higher grades of IPN. SMI ultrasound can detect neovascularization with CEUS-like accuracy, indicating that SMI is a promising noninvasive alternative to CEUS for carotid plaque stability assessments.
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