Carotid plaque neovascularization detected with superb microvascular imaging ultrasound without using contrast media
Stroke Nov 13, 2019
Zamani M, et al. - In this investigation including 31 individuals (22 were symptomatic and 9 asymptomatic) with > 50% carotid stenosis, researchers analyzed the feasibility of superb microvascular imaging for the detection of intraplaque neovascularization (IPN). All study participants had a conventional carotid ultrasound, CEUS, superb microvascular imaging (SMI), and blood tests. The data presented in this work showed a significant positive association between an IPN visual 5-level classification of SMI and a semiquantitative analysis of CEUS. Higher SMI grade plaques had higher numbers of neovessels quantified at histology. Hypoechoic plaques on both CEUS and SMI had higher grades of IPN. According to findings, SMI ultrasound can identify neovascularization with CEUS-like accuracy, indicating that SMI is a promising noninvasive alternative to CEUS for carotid plaque stability assessments.
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