Alexandrino AS, et al. – The authors undertook this work to compare the impact of caregivers’ health education regarding children’s respiratory infections and the effect of a rhinopharyngeal clearance protocol in children with upper respiratory tract infections (URTI). They concluded that the most positive impact on children’s health outcomes occurred when combining health education of caregivers, regarding children’s respiratory infections, with a rhinopharyngeal clearance protocol in children with URTI.

• This trial enrolled 138 children up to 3 years, attending day–care centres.
• Children were divided into four groups: control group (CG) (n = 38); education group (EG) (n = 34); intervention group (IG) (n = 35); and education and intervention group (E + IG) (n = 31).
• A Diary of Records was kept by caregivers during 1 month.
• There were significant differences between groups concerning: Lower Respiratory Tract Infections (CG = 29.4%; EG = 10.7%; IG = 3.8%; E + IG = 0.0%; p = 0.014); acute otitis media (CG = 32.4%; EG = 7.1%; IG = 11.5%; E + IG = 7.7%;p = 0.014); medical consultations (CG = 70.6%; EG = 42.9%; IG = 38.5%; E + IG = 30.8%; p = 0.021); antibiotics (CG = 44.1%; EG = 7.1%; IG = 23.1%; E + IG = 15.4%; p = 0.006); days missed from day–care (CG = 55 days; EG = 22 days; IG = 14 days; E + IG = 6 days; p = 0.020); days missed from employment (CG = 31 days; EG = 20 days; IG = 5 days; E + IG = 1 day; p = 0.021); and nasal clearance techniques (CG = 41.4%; EG = 78.6%; IG = 57.7%; E + IG = 84.6%; p = 0.011).