Ujvárosy D, et al. - Given that chest compression is a decisive element of cardio-pulmonary resuscitation (CPR) and compression interruptions can be minimised with a mechanical CPR device, researchers performed this retrospective, randomised 3-year study to assess the efficiency of manual and device-assisted resuscitation as well as the impacts of cardiovascular risk factors on resuscitation outcome in 287 adult patients suffering non-traumatic, out-of-hospital, sudden cardiac death (SCD). For 232 and 55 patients who received manual and device-assisted resuscitation (LUCAS-2), respectively, data were compared. Device-assisted resuscitation offered an insignificantly more favourable tendency to restoration of spontaneous circulation (ROSC). A possible role of advanced age and structural heart diseases in the genesis of SCD was suggested. A negative impact of left ventricular hypertrophy and hypertension on survival was evident.