Hakala JO, Pahkala K, Juonala M, et al. - Researchers examined the links of cardiovascular risk factors from childhood to midlife, their accumulation, and midlife cognitive performance. They performed repeated follow-up for 31 years in a population-based cohort of 3596 children (3–18 years of age) from 1980. In 2,026 participants 34 to 49 years of age, cognitive testing was conducted employing a computerized test. An inverse link with midlife cognitive performance was shown by the following factors: longitudinal increased systolic blood pressure, high serum total cholesterol, and obesity from childhood to midlife. The higher the number of cardiovascular risk factors, the worse was the noted cognitive performance. Thus, primordial promotion of cognitive health in adulthood might benefit from implementing prophylactic strategies against cardiovascular risk factors beginning from childhood.