Patel N, et al. - In patients with severe sepsis from 2012-2014 New York State Inpatient Database, researchers assessed the incidence of cardiovascular events and their relation to in-hospital mortality. They compared the risk of in-hospital mortality among severe sepsis patients with and without cardiovascular events by using multivariable logistic regression models. Among 117,418 patients (mean age, 70.8 years; 50.4% males, 59.5% whites) with severe sepsis, 31.7% developed new-onset (incident) cardiovascular event, 9.3% developed ischemic events, 6.9% had acute heart failure (HF) events, and 23.4% of patients suffered arrhythmic events. During the hospitalization, death of an estimated 32.9% of patients with severe sepsis was reported. Findings revealed 29% higher odds for in-hospital mortality in association with new-onset cardiovascular events among severe sepsis patients as compared with patients without cardiovascular events in multivariable adjusted model. Overall, a frequent occurrence of incident cardiovascular events was observed among patients with severe sepsis.