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Cardiovascular disease risk factor clustering in children and adolescents: A prospective cohort study

Archives of Diseases in Childhood Apr 19, 2018

Seo YG, et al. - The goal of this research was to determine risk factors for cardiovascular disease risk factor clustering (CVD-RFC) in order to prevent chronic disease in adolescents. Significant risk factors for the development of CVD-RFC in adolescents were obesity in childhood, short sleep duration and parental factors such as low socioeconomic status and parental history of CVD. Researchers creating awareness about sufficient sleep duration through intervention programs targeting cardiometabolic health in children, as well as special focus on lifestyle modifications and socioeconomic components of the family.

Methods

  • Data was obtained from school-aged children who participated in the Korean Child-Adolescent Study 2008-2014 for this prospective longitudinal cohort study.
  • Researchers recruited 1,309 children aged 6-15 years.
  • Enrollees were compared based on the presence or absence of CVD-RFC, then the cumulative incidence of CVD-RFC was analyzed.

Results

  • Among 1,309 children, 410 (31.32%) had CVD-RFC in adolescence.
  • Findings disclosed that a higher average household income ≥3 million Korean Republic won (KRW)/month was related to a lower CVD-RFC incidence (3-5 million KRW/month: HR 0.75 [95% CI 0.58 to 0.97]; ≥5 million KRW/month: HR 0.58 [95% CI 0.44 to 0.77]).
  • On the other hand, the presence of parental CVD history (HR 1.28 [95% CI 1.04 to 1.57]), overweight or obesity (HR 3.83 [95% CI 3.05 to 4.80]) and shorter sleep duration of 8-9 hour/day (HR 1.80 [95% CI 1.05 to 3.07]) and <8 hour/day (HR 1.93 [95% CI 1.11 to 3.34]) presented with higher CVD-RFC incidences.
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