Zhang H, Lin W, Chen D, et al. - This research sought to explore the causes of death in male breast cancer (MBC) patients. Researchers collected MBC patient data from the Surveillance, Epidemiology, and End Results database (1975– 2016). Using Joinpoint software, time trends of MBC mortality in the US population were examined. The proportion of each cause of death in the overall cohort and in different patient subgroups was calculated. They used competing risk models to compute cumulative mortality at different follow-up times. They compared the risk of cardiovascular death (CVD) in MBC patients to that of the age-matched general population by calculating the standardized mortality ratio (SMR). A total of 6,426 patients were enrolled in the analysis. According to the findings, non-breast cancer death accounts for the majority of deaths in MBC patients who are elderly or have localized cancer. MBC patients have an increased risk of CVD in comparison with the general population. These outcomes indicate the importance of monitoring cardiovascular comorbidities in MBC patients.