Berntsen KS, et Al. - Researchers assessed cardiorespiratory fitness (CRF) expressed as maximal oxygen uptake (VO_2max) among patients with long-term juvenile dermatomyositis (JDM; n=45) vs controls (n=45) and among patients with active vs inactive disease. They also evaluated exercise limiting factors and associations between CRF and disease variables. They observed lower CRF levels in JDM patients, both with active and inactive disease, vs controls after a mean 20 years of disease duration. Different limiting factors contributing to the reduced CRF according to disease activity, including deconditioning in inactive disease and reduced ventilatory capacity in active disease were suggested by cardiopulmonary exercise test results.