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Cardio‐metabolic risk factors during childhood in relation to lung function and asthma

Pediatric Allergy and Immunology Mar 31, 2021

Mensink‐Bout SM, Santos S, de Jongste JC, et al. - In this population‐based cohort study involving 4,988 children, researchers sought to study the longitudinal correlations of cardio‐metabolic risk factors with lung function and asthma at school‐age, as well as to examine whether any association was explained by child’s body mass index. At a median age of 6.0 years (95% range 5.6 – 7.6) and 9.8 years 109 (95% range 9.3 – 10.4), cardio-metabolic risk factors including blood pressure, lipids, insulin and 110 C‐reactive protein (CRP) concentrations have been measured. There were no consistent associations between other cardio-metabolic risk factors and respiratory outcomes. Lung function, but not asthma, was related to blood pressure and CRP, but not lipids or insulin. Further research into the underlying mechanisms and long-term consequences of these associations is required.

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