Mulder CL, Lassi ZS, Grieger JA, et al. - Utilizing PubMed, Embase and CINAHL, Scopus, and additional manual and bibliographic searches for relevant articles (end search date 6 November 2019), researchers conducted a systematic literature search to ascertain if infertile women have higher levels of cardiovascular risk factors vs fertile women. Compared with fertile women, there was an increased presence of several cardio‐metabolic risk factors in infertile women.  Compared with fertile women, infertile women had statistically significant higher BMI, increased total cholesterol (TC), low‐density lipoprotein cholesterol (LDL‐C) and triglycerides (TG). Fasting glucose, fasting insulin, homeostatic model assessment of insulin resistance and mean arterial pressure among fertile and infertile women were not found to differ. A subgroup analysis showed that TC, fasting glucose and fasting insulin were increased, and high‐density lipoprotein was only decreased in women with polycystic ovarian syndrome vs fertile women, while BMI, TG and LDL‐C were statistically significantly increased in women with any indication of infertility vs fertile women. This result generally has clinical consequences for infertile women, and those who attempt to conceive by medically assisted reproduction.