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Cardiac intravoxel incoherent motion diffusion‐weighted magnetic resonance imaging with T1 mapping to assess myocardial perfusion and fibrosis in systemic sclerosis: Association with cardiac events from a prospective cohort study

Arthritis & Rheumatology Aug 07, 2020

Terrier B, Dechartres A, Gouya H, et al. - This study was undertaken to investigate the usefulness of cardiac MRI with intravoxel incoherent motion (IVIM ) diffusion‐weighted imaging (DWI ) and longitudinal relaxation time (T1) sequence mapping for assessment of myocardial microvascular and interstitium impairment in systemic sclerosis (SS c). Researchers conducted a single‐center prospective cohort study including a total of 40 consecutive patients with SS c and 20 healthy controls were evaluated by cardiac MRI with IVIM DWI and T1 mapping sequences on a 3T scanning system. In patients with diffuse cutaneous SS c, elevated T1 values, potentially implying microscopic fibrosis, were observed more frequently, and higher T1 values were correlated with interstitial lung disease and more frequent cardiac events during follow‐up. The outcomes of this research exhibit that cardiac MRI with T1 mapping sequences and IVIM DWI may be useful in assessing myocardial involvement in patients with SS c.

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