Kim JY, et al. - Authors examined the significance of carbonic anhydrase 9 (CA9) and vimentin expression in the case of pancreatic neuroendocrine neoplasms/tumors (PanNETs). Findings revealed CA9 expression in normal islets, while neuroendocrine microadenomas and small (< 1 cm) PanNETs displayed loss of CA9 expression. Furthermore, it was noted that CA9 expression gradually reappeared in larger PanNETs. It appeared to be related to the clinical progression and decreased patient survival by univariate but not multivariate analysis.