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Cancer-attributable mortality among solid organ transplant recipients in the United States: 1987 through 2014

Cancer Aug 01, 2019

Noone AM, Pfeiffer RM, Dorgan JF, et al. - Researchers investigated deaths attributable to cancer among solid organ transplant recipients in the United States (1987-2014), by analyzing linked transplantation and cancer registry data. The development of cancer was reported in 15,012 of overall 221,962 solid organ transplant recipients examined. The cancer-attributable deaths were nearly 13%, corresponding to a cancer-attributable mortality rate of 516 per 100,000 person-years. Among solid organ transplant recipients, cancer was identified as a substantial cause of death. Lung cancer and non-Hodgkin lymphoma were identified as major contributors to cancer-attributable mortality. With age and time since transplantation, increases in cancer-attributable mortality were reported. This implies that an increasing burden will be posed by cancer deaths as recipients live longer.
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