Eklof V et al. - Microbial markers are a potential screening strategy for CRC.

Methods
A nested case-control study of 238 study subjects was adopted to investigate the use of microbial markers for clbA+ bacteria harbouring the pks pathogenicity island, afa-C+ diffusely adherent Escherichia coli harbouring the afa-1 operon, and Fusobacterium nucleatum in stool as potential screening markers for CRC. 

Results
Individual markers for clbA+ bacteria and Fusobacterium nucleatum were more abundant in stool of patients with CRC.
Cancer was predicted with a relatively high specificity (81.5% and 76.9%, respectively) and a sensitivity of 56.4% and 69.2%, respectively.
In a combined test of clbA+ bacteria and Fusobacterium nucleatum, CRC was detected with a specificity of 63.1% and a sensitivity of 84.6%.