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Can we corroborate peripapillary RNFL analysis with macular GCIPL analysis? our 2-year experience at a single-centre tertiary healthcare hospital using two OCT machines and a review of literature

Clinical Ophthalmology Nov 06, 2020

Abrol S, Gupta S, Naik M, et al. - This cross-sectional, observational study was undertaken to determine if macular volume and macular GCA measurements in patients are comparable to their RNFL thickness parameters. A sample of 1,380 eyes (460 eyes per group) including 10% non-response was taken. Using Shapiro–Wilk test, data were checked for normality before statistical analysis. In order to define the ability RNFL and GCC parameters to distinguish perimetric and preperimetric glaucomatous eyes from control eyes, receiver operating characteristic curves were used. RNFL analysis for diagnosis, serial monitoring and follow-up of glaucoma patients and suspects can be substantiated by mean, superior, inferior GCIPL thickness along with macular volume analysis.

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