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Can extraprostatic extension be predicted by tumor-capsule contact length in prostate cancer? relationship with international society of urological pathology grade groups

American Journal of Roentgenology Feb 27, 2020

Bakir B, et al. - This study intended to investigate the correlation between the tumor-capsule contact length, defined as tumor contact length (TCL), and extraprostatic extension (EPE) using the MRI-based TCL measurements and the real TCL measurements from pathology and to determine whether the International Society of Urological Pathology (ISUP) grade group of the tumors influenced this relationship. Between 2012 and 2018, researchers conducted prostate multiparametric MRI (mpMRI) studies of 1,576 patients and found that 134 patients also underwent radical prostatectomy (RP) after mpMRI. They applied ROC analysis to assess the cutoff values of TCLs measured at pathology and TCLs measured on MRI in terms of EPE according to ISUP grade groups. It was indicated that ISUP grade groups may have an impact on the TCL-EPE relationship. A cutoff value around 15–16 mm may be helpful to predict EPE when the MRI-based TCL and EPE association is estimated independently of the ISUP grade group.
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