Staiger RD, Gerns E, Castrejón Subirà M, et al. - Researchers examined whether specific patterns of early postoperative complications may allow prediction of overall severe morbidity after major surgery, warranting early escalation of care and prevention of failure to rescue. They analyzed all 90-day postoperative events after complex pancreas, liver, and rectal surgeries, and liver transplantation over a 3-year period in a single tertiary center. Findings suggest that multiple complications of any cause or severity within the first postoperative days are strongly linked with a severe postoperative course and represent a “warning-signal” for overall high morbidity by 90 days. These should be used to trigger an escalation of care to avert failure to rescue and eventually poor outcome.