Jonsson MK, et al. - The goal of this study was to assess the association of calprotectin with measures of disease activity, as well as its ability to predict treatment response and radiographic progression in patients with early rheumatoid arthritis (RA) patients. Findings demonstrated the correlation of calprotectin with inflammation assessed by ultrasound before and during disease-modifying antirheumatic drug (DMARD) treatment. Data also showed an association of calprotectin with radiographic progression. The data support that calprotectin may be of interest as an inflammatory marker when assessing disease activity in different stages of RA.