Kromhout MA, et al. – Researchers conducted a systematic review of seven studies to assess the link between caffeine consumption and neuropsychiatric symptoms in patients with dementia. These studies were identified from Medline (PubMed), Embase, Emcare, Cochrane, PsychInfo, Web of Science, and gray literature. They excluded studies involving subjects without a diagnosis of dementia, or those that presented a review or expert opinion. Sleeping difficulties and behavioral symptoms were reported in four and five studies, respectively. According to the findings, neuropsychiatric symptoms in individual patients with dementia could be either induced or attenuated by caffeine, and thus, a prudent individualized approach is needed for caffeine intake in these patients.