Xu WW, et al. - Researchers conducted a retrospective study of 414 newly-diagnosed diffuse large B-cell lymphoma (DLBCL) patients for estimating prognostic factors via establishing univariate and multivariate Cox proportional hazards models. Outcomes revealed unfavorable progression-free survival (PFS) and overall survival (OS) among patients with higher CAR [ratio of C-reactive protein to albumin] during a median follow-up of 40 months. CAR was validated to be an independent risk factor for both PFS and OS in multivariate Cox regression analysis. National Comprehensive Cancer Network -International Prognostic Index (NCCN-IPI) in combination with CAR vs NCCN-IPI alone showed a superior prognostic significance.