Schein ASO, et al. - In this cross-sectional study with 285 diabetic-hypertensive patients (aged 59 [54–62] years; 101 (35%) men), researchers investigated the link between C-reactive protein (CRP) and blood pressure (BP) variability. They assessed laboratory features and 24-hour ambulatory BP monitoring, as well as SD, coefficient of variation (CV%), time-rate index of 24-hour systolic BP (SBP), and 24-hour BP patterns. They performed comparisons between two groups, defined by CRP of up to 3 mg/l (low) and more than 3 mg/l (high). The high CRP group exhibited increased office SBP and DBP. No difference was found in BP variability indexes among groups. The high CRP group had higher BMI, total cholesterol, and HbA1c. Findings revealed a link between higher CRP levels and cardiometabolic derangements in patients with diabetes and hypertension, without any relation to increased BP variability.