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C-reactive protein/albumin ratio is a poor prognostic factor of esophagogastric junction and upper gastric cancer

Journal of Gastroenterology and Hepatology Feb 06, 2019

Kudou K, et al. - In patients who underwent surgery for adenocarcinoma of the esophagogastric junction (AEG) and upper gastric cancer (UGC), researchers examined the prognostic value of the C-reactive protein (CRP)/albumin (Alb) ratio, a novel prognostic marker in several cancers. For this investigation, they reviewed data for 144 subjects who had surgery for AEG and UGC. The study results showed that the optimal cut-off value of the CRP/Alb ratio was 0.1. In patients with a CRP/Alb ratio ≥ 0.1, they observed that the 5-year recurrence-free survival and overall survival rates were significantly lower vs those with a CRP/Alb ratio < 0.1. In patients who underwent surgery for AEG and UGC, the CRP/Alb ratio was strongly related to poor prognosis.

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