Burden and disease characteristics of patients with psoriatic arthritis: A population-based cross-sectional study
The Journal of Rheumatology Jul 05, 2019
Tekin HG, et al. - Via all Danish people aged ≥ 18 years with rheumatologist-diagnosed psoriatic arthritis (PsA) were linked in nationwide administrative registers by the researchers in order to illustrate the prevalence and treatment regimes, disease characteristics, and comorbid diseases in 10,577 patients (as diagnosed by a rheumatologist) with PsA in Denmark. Almost half of the patients had taken no treatment or treatment only with nonsteroidal anti-inflammatory drugs/systemic corticosteroids with a female majority. Nonbiological disease-modifying antirheumatic drugs were taken by 32.9% of the patients and 14.1% had been treated with physicians. About 66.2–72.3% of cases with PsA were registered with cutaneous psoriasis. The maximum prevalence of distal interphalangeal arthropathy, spondylitis, and arthritis mutilans was observed in patients with severe PsA. In patients with PsA, smoking and co-occurring diseases such as hypertension, diabetes, depression, and anxiety were commonly noted, however, it did not markedly differ across severities of PsA. Hence, in patients with PsA, disease burden seemed to be significant through all severities. No active antipsoriatic treatment was obtained by a considerable proportion of cases with PsA with no diagnosis in 1 out of 3 patients. Further, there could be a possibility that cutaneous symptoms of psoriasis in patients with PsA could be either underreported or undertreated.
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